* [[Charlie Bradbury]] (deceased) - An ally of the Winchester boys. Dean claims that "She's kind of like the little sister I never wanted." Even Charlie considered the Winchester boys her brothers.
* [[Kevin Tran]] (deceased) - Dean tells Kevin that after everything he's been through with them, Dean considers Kevin a member of the family and that each other, Sam and Castiel are all they have left in the world. Kevin apparently considers Dean the same as he stays when Dean tells him to leave if that means nothing to him.<ref>[[9.02 Devil May Care]]</ref>
* [[Jack Kline]] - Sam cares about Jack and thinks of him as a little brother as they both understand what it feels like to be different.<ref>[[13.03 Patience]]</ref><ref>[[13.04 The Big Empty]]</ref> After a rocky start, Dean eventually accepts Jack as well, even including him in [[Team Free Will]]. Later, Jack reciprocates these feelings, stating that Sam, Dean, and Castiel are all he has and can't see them get hurt.<ref>[[13.06 Tombstone]]</ref> Later Jack proclaims himself a Winchester. <ref>[[14.14 Ouroboros]]</ref>
* The [[Impala]] - Definitely a member of the family. Before moving into the [[Men of Letters Bunker]], the car acted as Sam and Dean's home.