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==Trivia==
* In [[2.06 No Exit]] and [[14.13 Lebanon]], Sam and Dean face the [[ghost]]s of famous serial killers [[H.H. Holmes]] and [[John Wayne Gacy]], respectively, who continue their murder sprees after death. Both ghosts are defeated by the Winchesters and prevented from causing further harm.
*In the non-canon novel ''[[Supernatural: Nevermore]]'', the main bad guy is a serial killer named Ross Vincent. In addition, in ''[[Supernatural: Night Terror]]'', the deranged serial killer Kurt Machalek and the deranged and cannibalistic serial killer Ragnar Bartch appears. In ''[[Supernatural: Cold Fire]]'', the pontianak, Riza Nodd, is the daughter of secret serial killer Calvin Nodd whose murder of her, her unborn child and her boyfriend turned Riza into a monster in the first place.
*The Winchesters have to deal the [[vengeful spirit]]s of deceased serial killers George Drechler and Clive Gillmer in ''[[Supernatural: Fresh Meat]]'' and ''[[Supernatural: Night Terror]]'' respectively.
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