Sedation

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Sedation is the ability of angels to render someone unconscious. This also extends to nephilim.

Episodes

4.01 Lazarus Rising

When Bobby meets Castiel for the first time, he sees him as a threat and attempts to attack. Castiel sedates him.

4.10 Heaven and Hell

Castiel sedates Sam when he gets in the way of capturing Anna Milton.

5.13 The Song Remains the Same

In order to talk to Dean alone, Michael sedates Mary.

12.19 The Future

Castiel sedates Sam and Dean in an attempt to ensure that Lucifer's son is born.

13.09 The Bad Place

The nephilim Jack attempts to free Kaia from a drug treatment facility and sedates a staff member who attempts to stop them.