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Sedation is the ability used by angels to render someone unconscious.


4.01 Lazarus Rising

When Bobby meets Castiel for the first time, he sees him as a threat and attempts to attack. Castiel sedates him.

4.10 Heaven and Hell

Castiel sedates Sam when he gets in the way of capturing Anna Milton.

12.19 The Future

Castiel sedates Sam and Dean in an attempt to ensure that Lucifer's son is born.