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==History==
[[File:Mark of Cain Location Spell.png|thumb|right|350px|Manuscript on the location spell for the Mark of Cain.]]
According to [[Death]], before there was life, the Earth, or even God and the [[archangels]], there was [[the Darkness]]. God and His archangels defeated the Darkness and locked it away rather than destroy her to maintain [[the Cosmic Balance]]. God created the Mark to act as the lock and key on to the Darkness' cage and if it is was to destroyed, the Darkness will would be released. God gave the Mark to his most trusted lieutenant, [[Lucifer]], but the Mark corrupted Lucifer and made him jealous of humanity which led to his imprisonment in [[Lucifer's Cage|the Cage]]. Prior to being locked away, Lucifer eventually passed the Mark to [[Cain]] as part of his deal to save Abel from Lucifer's influence.
After Cain was given the Mark, he begins began to realize what kind of toll bearing the Mark will would take after he killed Abel, and rather than be controlled by his murderous compulsion, he attempts attempted to kill himself with the First Blade. However the Mark would not let his [[soul ]] depart to the afterlife. After Cain's soul was twisted and corrupted by the Mark's dark, influential, primal energies, he was reborn as a [[Knight of Hell]], the very first of his kind. He goes Cain would go on to train and lead souls handpicked by Lucifer to be the Knights of Hell under Lucifer's command, as they wreacked and would wreaked havoc on Earth for centuries as the harbingers of chaos and darkness.<ref name="nine11">[[9.11 First Born]]</ref> .
After centuries of murder and mayhem, he Cain fell in love with [[Colette Mullen]]. The Knights took retribution and took Colette, so forcing Cain used to use the First Blade and its energy drawn from the Mark to slaughter all the Knights except for one; [[Abaddon]]. Despite Colette's death by Abaddon's hands, Cain manages managed to cease killing, keeping his final promise to herhid wife. After burying his wife, after he Cain disposed of the First Blade in the Mariana Trench.
===Powers===
The Mark is the source of [[the First Blade]]'s power, and imbues its owner with great strength and an almost insatiable desire to kill. This strength is enough to overpower an entire nest of [[vampires]] and even [[Castiel|an angel]]. It is the source of [[the First Blade]]'s power. The Mark and the Blade work together, and without it the First Blade is rendered useless. The Mark can also be transferred to someone else if the person is worthy of it; a killer like Cain. While the Mark is a corrupting influence, [[God]] revealed to Lucifer that the Mark does not change the bearer, but merely amplifies and intensifies what is already there. Which in Lucifer's case was his dislike of humanity.
The Mark will act to prevent the person who holds it from being killed, even by their own hand such as blocking fatal spells and preventing the person from committing suicide even during a hallucination.
The bearer of the Mark has also demonstrated other powers such as a [[telekinesis|telekinetic]] control of the First Blade, immunity to demonic powers with great concentration and in at least one case, premonitions of the murders the Mark will make them commit. It also resurrects the user as a [[Knight of Hell]] if they die.
The Mark's existence keeps [[the Darkness]] bound. If it is removedwithout being transferred to someone else, the Darkness will be released from its confinement.
==Dean and the Mark==
In order to kill [[Abaddon]], Dean decided to take on the Mark in order to be able to wield [[the First Blade]]. He agreed to take on the Mark despite [[Cain]]'s warnings of a terrible price as he was eager to kill Abaddon and didn't care what the price would be.
After gaining the Mark, [[Dean]] began to exhibit more aggressive behavior, and once the Mark was activated by the First Blade his aggression was amplified. Once he began killing with the First Blade, the burden of the Mark became apparent -- the more Dean kills the better he will feel, the less he kills the worse he will feel, and if he does not keep killing it will eventually cause his death. Because , as Crowley informs Dean, the human body was never meant to contain the First Blade's power.
After [[Metatron]] kills him, Dean is resurrected by the power of the Mark and the First Blade. It has , which twisted his soul until it is was demonic. As a demon Dean shows showed no care for anyone or thing -- not even Samor the Impala. The Mark of Cain also bestows bestowed an invincibility onto Dean's body, which has been shown to be able to heal from any wounds inflicted upon it. Crowley reveals to Dean that the Mark needs to be sated with killing, or Dean will become even darker.
Sam is was able to [[Demon Cure|cure]] Dean and revert him of being back to a Knighthuman, however, he Dean still possesses possessed the Mark. After seemingly being unaffected by the Mark for months, its powers started to affect Dean again, giving him a precognitive nightmare of a massacre of humans he committed under its influence a few days later. Unable to find any way in the lore to stop the Mark's influence, Castiel retrieved Metatron from his incarceration in Heaven. Metatron refused to provide any information, however as Dean tortured him, Metatron tells him, "The river shall end at the source." Sam suggests to Dean that he needs to find a power within himself to resist the influence of the Mark.
==Episodes==