Jesus

Castiel: Your Bible gets more wrong than it does right. – , 5.06 I Believe the Children Are Our Future

Jesus is mentioned rarely in Supernatural, and held to be a man not a deity, although he's held responsible for being at the core of Christianity, a religion that surplanted many earlier religions and deities.

Dean sometimes refers to Holy Water as "Jesus Juice".

3.08 A Very Supernatural Christmas

Edward Carrigan: All of a sudden, this Jesus character is the hot new thing in town. All of a sudden, our – our altars are being burned down, and we’re being hunted down like common monsters.

Madge and Edward Carrigan are Pagan Gods disguised as a suburban couple. They blame Christianity for their marginalisation.

6.16 ...And Then There Were None

Eve: You do know that Jesus was just a man.

Eve, the mother of all monsters, tells Rick, a devout truck driver, that Jesus was only a man, and that God has abandoned humanity.

9.08 Rock and a Hard Place

Vesta: ...that hippie dude from Bethlehem.

Vesta blames Jesus and Christianity for the diminishing in her prominence.

Jesus in Lore

Jesus is held to be a manifestation of God as a human. The religion of Christianity is centred on belief that his death provided atonement for sin. He may have been an actual historical figure, a Jewish teacher who lived in Palestine. Jesus is held to be a prophet in Islam.