|Dates||???? - 2007 (killed by Gluttony)|
|Location||Near Lincoln, Nebraska|
|Episode(s)||3.01 The Magnificent Seven|
Isaac is a hunter who lives and works near Lincoln, Nebraska, with his wife Tamara. They have been hunting for eight years, after something supernatural killed their daughter. At some point during those eight years, they met and befriended Bobby Singer. Isaac is seen carrying a pump action shotgun and a flask of holy water. He and his wife also have Palo Santo ("holy wood") and a house full of odds and ends that as of yet are unidentified.
Upon meeting the Winchesters, Isaac is reluctant to work with them, blaming them for opening the Devil's Gate and bringing about the end of the world, showing he is more quick to anger than his wife. While investigating a bar looking for demons, the couple believes they have spotted one, and Isaac with a flask of holy water attempts to make a move, until he is stopped by the bartender who reveals himself a demon. Surrounded by the Seven Deadly Sins, the demon Gluttony forces him to down a bottle of Drano, killing him while Tamara watches in vain. Bobby soon arrives, crashes his car through the bar just in time to save Tamara, who is forced to abandon Isaac's body during the escape.
When they get back to the house, a demon possessing Isaac's corpse tries to trick Tamara into letting him into the house, but she stabs him and drives out the demon with a stake of Palo Santo. In the morning, he is given a hunter's funeral pyre by Tamara.