Hand of Glory
The Hand of Glory is hand of a murderer, removed while he is on the gallows and then pickled and dried. When used with candles made from the fat of a murder, it was said to render people unable to move. It was also said to able to unlock any door, thus making it useful for thieves.
Bela steals the Hand of Glory from the Sea Pines Maritime Museum. It is haunted by a vengeful spirit whose hand it belonged to in life. The spirit was hanged for treason on a ship captained by his brother; thus he takes vengeance on people responsible for the death of family members.
While visiting a pawn shop, the owner shows the Winchesters a Hand of Glory amongst his collection. After killing the man, Sam and Dean take the Hand of Glory along with his collection of other occult objects.