Used in old voodoo practice, it is a mixture of natural ingredients that can be used to cause harm, trouble or even kill. The word goofer comes from the Kikongo word "kufwa" which means "to die". As late as the 1930s, "goofering" was a regional synonym for voodooing, and the meaning of the term was broadened beyond spells of damage, illness and death to include love spells cast with a dominating intent.
Often used synonymously with graveyard dirt, which is usually the primary ingredient along with snakeskin and sulfur, goofer dust is used to keep hellhounds at bay, as they won't cross it until the line or circle is broken. However, it has no effects on high ranking demons such as Lilith, who was able to open a door and break its barrier with no effort.
Goofer dust. What, you boys think you know somethin' about somethin' but not Goofer dust? [...] Hoodoo. My grandma taught me. Keeps out demons.