Drugs

Dean: Uh, should we dim the lights and sync up Wizard of Oz to Dark Side of the Moon? Sam: Why? Dean: What did you do during college? – Sam and Dean, 3.10 Dream a Little Dream of Me

The theme of addiction is recurrent throughout Supernatural, and recreational drugs are no exception. Though alcohol is the drug of choice for hunters, civilians in the series are often shown as turning to marijuana and prescription drugs for escapism. No characters are shown smoking or snorting any illegal substances in the series, but Dean has a running commentary on drugs, both in joking reference to other characters's paraphernalia and by alluding to his own history with illegal substances.

Episodes

2.05 Simon Said

In Andy's van, Sam and Dean find a very large piece of drug paraphernalia, which Dean refers to as "Moby Dick's bong."

2.21 All Hell Breaks Loose: Part One

When Sam meets up with Andy Gallagher at Cold Oak he asks Andy what the last thing he remembered before waking up there. Andy replies "My fourth bong load."

3.08 A Very Supernatural Christmas

As Sam and Dean hunt for an "Evil Santa" they follow the Santa from a Christmas village to his home. They enter, armed, but find a disheveled "Santa" watching Christmas-themed porn while drinking smoking a large bong and a bottle of liquor in hand.

3.10 Dream a Little Dream of Me

Because of the use of African Dream Root, there are frequent references to drugs and stoner culture throughout this episode.

4.07 It's the Great Pumpkin, Sam Winchester

When Sam and Dean go to interview Don Harding Dean sees Justin, who is putting a big bong-shaped piece into a kiln. "Now that brings back memories," he remarks.

4.10 Heaven and Hell

When Anna tells Dean she can take her grace back in and become an angel again, Dean responds: "So what, you're just gonna take some divine bong hit, and Shazam, you're Roma Downey?"

5.04 The End

In Zachariah's vision of a post-apocalyptic future, Castiel is no longer an angel and has turned to sex, alcohol, and prescription drugs as a means of escapism. Upon meeting him, Dean asks if Castiel is stoned. Castiel's response is, "Generally."

8.04 Bitten

There is a large bong in Michael Wheeler and Brian Wilcox's house. After hearing Sam and Dean speculate that the creature responsible for recent deaths may be a Mayan god, Michael (who has become a werewolf) holds the bong aloft and declares: "I am a golden god. I am a golden god!"

11.11 Into the Mystic

While investigating a nursing home for a case, Sam and Dean discover that one of the residents has been stealing Viagra from his neighbors. "A real dick move, huh?" Dean says, before pocketing a bottle while Sam is looking the other way.