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==Instructions==
The ritual must be performed over consecrated ground. The person performing the ritual can use either their own purified blood (after going to confessional) or sanctified blood (donated blood blessed by a priest). One universal symptom of both renditions of the cure is that the demon may experience pain while undergoing the injections as seen with [[Peter Kent]] and [[Dean Winchester]].
Purified blood must be injected into the demon every hour for eight hours. As the ritual progresses, the demon may begin expressing human emotions in the process. After the eighth dose is administered, the following exorcism must be recited:
<blockquote>
''Exorcizamus te, omnis immundus spiritus''<br>
''hanc animam redintegra''<br>
''lustra!'' (slice your hand and place it over the demon's mouth)<br>
''lustra!''
</blockquote>
After this, the demon will become human once more.
The use of sanctified blood does not require the exorcism to be recited nor does it affect Dean's demonic mannerisms, even though the cure progresses with turning him back to human enough to remove the [[Angel Cuffs|warded handcuffs]] and walk across the devil's trap in [[the Bunker]]'s dungeon. Only when the final dose is administered does his behavior return to normal.
According to [[Sam]], there are no exceptions to the cure, which is proven to be true when he cures Dean of being a [[Knight of Hell]], even while bearing the [[Mark of Cain]].
==Episodes==
===[[8.22 Clip Show]]===
Looking through the [[Men of Letters Bunker]]'s archives, [[Sam]] and [[Dean]] find a film where two priests, [[Father Max Thompson]] and [[Father Simon]] try a different type of [[exorcism]] on a [[possessed]] old woman. The result is that the woman's chest is burst open. Talking to the Father Simon, they discover that Father Thompson believed it was possible to cure a [[demon]] and turn them human again and the ritual was being used to that effect but failed. Listening to a recording of the last attempt Father Thompson made two days before he died, Sam and Dean learn that he finally succeeded by, on consecrated ground, injecting a demon with his own blood, purified by confession, over a period of eight hours until the demon began to sound human then performed the exorcism while putting his bloody hand over the demon's mouth. The demon became human again.
Sam and Dean set out to try the cure on [[Abaddon]], but she escapes when they are distracted by [[Crowley]] calling to threaten to kill all of the people they have ever saved if they don't hand over the [[demon tablet]] and back down from the trials. He also starts keeping all demons away from the Winchesters as he has realized they may need one for the third [[trial]] and with no Abaddon, Sam and Dean are left without a demon to cure.
[[File:SamCuringCrowley.jpg|thumb|left|350px|[[Sam]] about to complete the ritual, and cure [[Crowley]].]]
===[[8.23 Sacrifice]]===
After Crowley starts killing all the people they have saved, Sam and Dean pretend to make a [[Deals and Pacts|deal]] with him. At the ruins of [[Singer Salvage Yard]], Sam shows Crowley the [[demon tablet]] to prove he has it while Crowley shows them the angel tablet. Crowley produces a contract many yards long, and Dean insists on reading the fine detail. As he does, he gets close to Crowley and snaps handcuffs on him connecting him to Dean. Crowley is initially amused until they reveal that they have carved a binding spell on them, keeping Crowley trapped and powerless. Sam and Dean take Crowley to a small church to undergo the third Trial - curing him.[[File:SamCuringCrowley.jpg|thumb|left|350px|[[Sam]] about to complete the ritual, and cure [[Crowley]].]]
Soon [[Castiel]] arrives, telling Dean he needs his help in undertaking the [[Heaven]] trials. Dean is reluctant to go, but Sam insists he will be fine. After confessing his sins, Sam starts injecting Crowley with his blood. After each injection, Sam's arms start glowing for a short period of time. At one point Crowley bites Sam, and when he leaves to get a bandage, Crowley casts a spell and uses the blood to send a call for help. Abaddon arrives, and throws Sam through a window, but she tells Crowley she is not there to help him, but to take over ruling Hell. But Sam douses her [[meatsuit]] with [[holy oil]], setting her on fire. Abaddon is left in such pain she abandons her body and flees the scene. Crowley starts regaining his humanity and tries to bond with Sam, tearfully declaring that he deserves to loved and wonders how he could even begin to ask for forgiveness for his actions. Sam suggests he start by going along with the cure and he willingly allows Sam to give him the next injection.