Apocalypse

Kansas City

In Supernatural, the Apocalypse also known as Armageddon is started when The 66 Seals that bind Lucifer are broken and he is freed.

• The first seal is broken when a righteous Man sheds blood in Hell; Dean ends up breaking the first seal when he spills the blood of a human soul in Hell.

• The last seal by was broken by Sam when he kills Lilith, Lucifer's first Demon.

Many angels including Zachariah and Michael wanted the 66 Seals broken. They believed that this would give Michael the opportunity to kill his younger brother, Lucifer. It is implied by both Castiel and Zachariah that Dean will stop Lucifer. Zachariah later revels that Dean alone cannot possibly stop Lucifer, but he tells Dean that he is Michael's true Vessel.

Four Horsemen of the Apocalypse and the Croatoan Virus are part of the demonic plan to cause death and chaos on Earth.

• It was up to Pestilence to spread the Croatoan Virus upon humanity. Status Of Procedure: partial success. However, according to Zachariah's futuristic vision, the demonic virus infected 90% of the Earth's population in the span of Five years (2009 to 2014). Zachariah's prediction ended up not happening.
• It was up to War to manipulate the perception of Humans in order to make humanity fight one another. Status Of Procedure: partial success.
• It was up to Famine to "ride" across the lands with authority and power. Status Of Procedure: failure.
• Lucifer hexed Death by casting a binding spell upon him. Lucifer then attempted to manipulate Death into wiping out 3,000,000 people by sending a "great storm" upon them. Death however decided to deny this order, he said it was because he like the Pizza distributed by Chicago. Status Of Procedure: failure

According to the vision of the future that Zachariah gives Dean in 5.04 The End, the intended trajectory involves the Croatoan Virus as a key part in the elimination of humanity. Apparently in 5.04 The End, all of Heaven bailed and left Earth to be overtaken/ruled by Satan, which would ultimately result in the extermination mankind. In the present the Croatoan virus was released, however this Virus didn't infect the entire World as it did in the 2014 future. Pestilence played an enormous role in eliminating Humanity. However, he was permanently neutralized by Castiel.

Zachariah may have given Dean a false prediction of 2014. This was proven in 5.22 Swan Song. Due to the circumstances that were reveled in episode 5.22 Swan Song, we could be led to believe that Zachariah did in fact give Dean a false vision of 2014. 5.04 The End and 5.22 Swan Song had two very different outcomes.

The Apocalypse in Fandom

• see Post-Apocalypse fanfic