While never explicitly stated, it is strongly suggested that sexual violence and rape are tools of torture in Hell. On a number of occasions Dean makes veiled references to it and Lucifer strongly hints that he sexually abused Sam while he was in [[Lucifer's Cage]].
There are broader issues related to dubious or non consensual acts throughout the show particularly related to the possession of humans by both angels and demons,
as well as the use of "love spells" in [[4.08 Wishful Thinking]] and [[7.08 Season Seven, Time for a Wedding!]].
There are number of fan essays written on these topics linked on the [[Meta Essays]] entry.