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|image= [[Image:Promo pic for 5.08.jpg|300px350px]]

'''Dean:''' Hey there , Sam. What's happening?<br>'''Sam:''' Oh , nothing. Uhm..Um. Just the end of the world.

'''SamDean:''' What are you watching? We have some more research to do.<br>'''DeanSam:''' A hospital show - ''Dr. Sexy, MDean.D.''. I think it's based on a book.<br>'''SamDean:''' When did you hit menopause?Son of a bitch!}}

'''Dean:''' That's doctor Piccolo. Doctor Ellen Piccolo, the sexy, yet earnest doctor, at... Seattle Mercy Hospital.<br>'''Sam:''' Aah... Dean? What the hell are you talking aboutwatching?<br>'''Dean:''' The doctor get-ups, the- the sexy interns, the 'seriouslys'..Hospital show. It all makes sense.<br>'''Sam:''' What makes sense? What's going on?<br>'''Dean:''' We're ''in'' ''Dr. Sexy, MMD.D.''}}{{TriviaQuote |Text='''Dean:''' And there's Johnny Drake. Oh he's not even alive, heI think it's based on a ghost in the mind of... of her. The sexy, but neurotic doctor over therebook.<br>'''Sam:''' So... this show has ghosts? WhyWhen did you hit menopause?<br>'''Dean:''' I don't know. It ''is'' compellings called channel surfing.

'''Dean:''' You're not Dr. Sexy.<br>'''Dr. Sexy:''' You're crazy.<br>'''Dean:''' Really? Because I swore part of what makes Dr. Sexy sexy is the fact that he wears cowboy boots. Not tennis shoes.<br>'''Sam:''' I need Yeah. You're not a pen knife, some dental floss, fan.<br>'''Dean:''' It's a sewing needle, and a fifth of whiskeyguilty pleasure. Stat!

'''Game show hostSam:''' NoOkay. Um. I need a penknife, no - Mr. Trickster does not like pretty boy angelssome dental floss, a sewing needle, and a fifth of whiskey.Stat!

'''TricksterSam:''' Oh, you know... Sam starring as Lucifer, Dean starring as MichaelI've got genital herpes. Your celebrity death match!

'''Sam:''' You've got to calm down.<br>'''Dean:''' Calm down? I'm wearing sunglasses at night. You know who does that? No talent douchebags. I hate this game. I hate that we're in a procedural cop show and you want to wanna know why? Because I hate procedural cop shows. There's like 300 three hundred of them on television, and they're all the freaking same, it. It's like 'oh... a ooh, plane crashed here.' Oh here—oh shut up!.

'''Forensic guyGabriel:''' Well... aside from the ligature marks around his neckplayed, he has what appears to be a roll of quarters jammed down his throatboys.<br>'''Sam:''' Well I say... jackpot.<br>'''Forensic guy:''' Hehplayed. Also thereWhere's a stabwound to d you get the lower abdomen there.holy oil?<br>'''Dean:''' Well I , you might say... No guts, no glorywe pulled it out of Sam's ass.

'''GabrielDean:''' Where did Do you get the holy oilblame him?I mean, his brothers are heavyweight douchenozzles.<br>'''DeanGabriel:'''Shut your cakehole. You don': Wellt know anything about my family. I love my father, you might say we pulled my brothers. Love them. But watching them turn on each other? Tear at each other's throats? I couldn't bear it! Okay? So I left. And now it out of Sam's asshappening all over again.<br>

'''GabrielDean:''' You All that stuff he was spouting in there, you think it was the truth?<br>'''Sam:''' I think he believes it.<br>'''Dean:''' So what do not we do?<br>'''Sam:''' I don't know my family. What <br>'''Dean:''' Well I'll tell you guys call the Apocalypseone thing. Right about now I wish I was back in a TV show.<br>'''Sam:''' Yeah, I call Sunday dinner!me too.

'''Gabriel[http:''' This isn't about a war//www. It's about two brothers that loved each other, and betrayed each otheryoutube. You think you'd be able to relate.<br>com/watch?v=qJbqZoZv_Ws Sitcoms have] been around since TV began from shows such as ''I Love Lucy'Sam:'through to '' What are you talking about?<br>Two and a Half Men'''Gabriel. They were often aired with a pre-recorded [http:''' (whistles) You sorry sons of bitches//en. Why do you think you two are the vessels? Think about itwikipedia. Michaelorg/wiki/Laugh_track laugh track], although in the big brother, loyal to an absent father. And Lucifer, the little brother, rebellious of daddy's plan. You were born to last decade this, boys. It's your destiny. It was always you. As it is in heaven, so it must be on Earth. One brother has to kill the otherbecome a less common practice.

[http'''Dean://www''' Well, it turns out that Bill Randolph had quite the temper.youtubeHe's got two counts of spousal battery, bar brawls, and court-ordered anger management sessions.com/watch?v=qJbqZoZv_Ws Sitcoms have] been around since TV began from shows such as You might say you wouldn't like him when he'I Love Lucys angry.:The wife of the first victim reports seeing '' through to The Incredible Hulk''Two - and the line Dean quotes is a Half Men''classic from the TV show and movies. They were often aired with a pre-recorded [http://en.wikipedia.org/wiki/Laugh_track laugh trackLou_Ferrigno Lou Ferrigno] starred as David Banner's (played by [http://www.imdb.com/name/nm0084642/ Bill Bixby], hulky green alter ego. [http://www.imdb.com/name/nm0051509/ Eric Bana] played Bruce Banner in the [http://www.imdb.com/name/nm0051509/ 2003 movie ''Hulk''], although and [http://www.imdb.com/name/nm0001570/ Ed Norton] played him in the last decade this has become a less common practice[http://www.imdb.com/title/tt0800080/ 2008 ''Incredible Hulk'']. The actual Hulk was basically CGI in these movies. ''

'''DeanSam:''' You might say you wouldnOkay, Trickster's like a Hugh Hefner type, right? Wine, women, song—maybe he doesn't like him when want the party to end. Maybe he hates this angels and demons stuff as much as we do. Maybe he's angry?<br>ll help us.:The wife of the first victim reports seeing ''The Incredible Hulk'' - and the line Dean quotes is a classic from the TV show and movies.[http://en.wikipedia.org/wiki/Lou_Ferrigno Lou FerrignoHugh_Hefner Hugh Hefner] starred as David Banner's (played by [http://www.imdb.com/name/nm0084642/ Bill Bixby], hulky green alter ego. [http://www.imdb.com/name/nm0051509/ Eric Bana] played Bruce Banner in is the [http://www.imdb.com/name/nm0051509/ 2003 movie ''Hulk'']publisher of Playboy Magazine, and [http://www.imdb.com/name/nm0001570/ Ed Norton] played him in the [http://www.imdb.com/title/tt0800080/ 2008 ''Incredible Hulk'']. The actual Hulk was basically CGI in these moviesknown for his extravagant lifestyle.''

'''Dean:''' A bloody , violent monster , and you want to wanna be [[Facebook]] friends with him?<br>Nice, Sammy.

''[[Dr. Sexy M.D.]]'' - hospital show set at Seattle Mercy Hospital - is a send-up of [http://en.wikipedia.org/wiki/Grey%27s_anatomy ''Grey's Anatomy''] a medical drama which aired opposite ''Supernatural'' in the U.S. on Thursday nights, revolving around the love lives of the staff of Seattle Grace Hospital. Dr. Derek Shepherd, played by Patrick Dempsey, is nicknamed [http://www.urbandictionary.com/define.php?term=Mcdreamy "McDreamy"] by other characters on the show. The scenes and melodramatic dialogue mimic that of ''Grey's Anatomy'' - as can be seen in [http://www.youtube.com/watch?v=7QiYtEpMKHQ these video clips.].

{{TriviaQuote |Text= The character Johnny Drake on ''Dr. Sexy, M.D'' is a take-off of the patient [http://en.wikipedia.org/wiki/Denny_Duquette Denny Duquette] on [http://en.wikipedia.org/wiki/Grey%27s_anatomy ''Grey's Anatomy'' ]. He had a romance with intern [http://en.wikipedia.org/wiki/Izzie_Stevens Izzie Stevens], but then died. Denny was first mentioned as played by none other than [[Jeffrey Dean Morgan]], a.k.a book series in . [[4John Winchester]].18 The Monster at the End In a classic case of This Book[[Surprise JDM]] by the publisher as one of the reasons the , he later returned twice to ''Grey's Anatomy'Supernatural'as a hallucination brought on by Izzie' books went out of prints brain tumor.

The character Johnny Drake on ''Dr. Sexy, M.D'' Nutcracker! is a take-off of the patient reference to [http://en.wikipedia.org/wiki/Denny_Duquette Denny DuquetteJapanese_game_shows Japanese game shows] on which are known for their weird, often humiliating and painful stunts. On the show [http://enwww.wikipediayoutube.orgcom/wiki/Grey%27s_anatomy watch?v=qJbqZoZv_Ws ''Grey's AnatomySay This Right! Nut Cracker'']. He had , contestants have to recite a romance tongue-twister, and if they get it wrong they get hit in the nuts with intern a ball on a stick!}}{{TriviaQuote |Text=[http://enwww.wikipediayoutube.orgcom/wiki/Izzie_Stevens Izzie Stevenswatch?v=Oy17dtyskyU The ad for "Herpexia"], but then died. Denny was played by none other than is a spoof of the [[Jeffrey Dean Morgan]], ahttp://www.kyoutube.a. [[John Winchester]]. In a classic case of [[Surprise JDMcom/watch?v=_iLTfG75s6g ad for Valtrex]], he later returned twice to ''Grey's Anatomy'' as a hallucination brought on by Izzie's brain tumorgenital herpes treatment.

'''Trickster:''' Oh, you know. Sam starring as Lucifer. Dean starring as Michael. Your celebrity death match. Play your roles.:''[http://en.wikipedia.org/wiki/Japanese_game_shows Japanese Game ShowsCelebrity_Deathmatch Celebrity Deathmatch] are known for their weirdwas a claymation series, often humiliating that involved celebrities fighting to the death that aired on MTV from 1998-2002 and painful stunts2006-2007. On the show [http://www.youtube.com/watch?v=qJbqZoZv_Ws ''Say This Right! Nut Cracker''], contestants have to recite a tongue-twister, and if they get it wrong they get hit in the nuts with a ball on a stick!

The "procedural cop shows" Dean refers to include shows like the ''CSI'' and ''Law and Order'' franchises. Like ''Grey's Anatomy'', ''CSI: Crime Scene Investigation'' aired in the U.S. at the same time as ''Supernatural'' on Thursday night. They specifically reference ''CSI: Miami'''s David Caruso's character, crime lab lieutenant [http://en.wikipedia.org/wiki/Horatio_Caine Horatio Caine.]. Sam and Dean mimic his mannerisms, demonstrated in this [http://www.youtube.com/watch?v=_sarYH0z948 video clip] and [http://www.youtube.com/watch?v=GeeyWvo1rNg this one] of taking his sunglasses on and off and turning to profile, and/or looking into the middle-distance as he makes makes a pithy observation about the crime. However, if you look closely to the badge one of the techs is wearing, it says LVPD (Las Vegas Police Department) specifically referencing ''CSI: Crime Scene Investigation'' which takes place in Las Vegas (the first in the ''CSI'' franchise).

At [[Salute to Supernatural Chicago 2009]] [[Jensen ]] and [[Jared ]] revealed that they'd watched the "Horatio" one-liners on YouTube in preparation for the scenes. They said that for years on ''Supernatural'' there'd been a running joke if a line was a bit "on the nose" that they'd send it up in this way. The lines "a plane crashed here" and "no talent douchebags" were adlibbed by Jensen ([http://www.youtube.com/watch?v=-XZsoXjtvU0 Sourceadlibbed by Jensen.]).

The mini bikes the boys are seen riding in the opening credits are actually mini bikes they ride around on set.[http://wwwphotos.youtubelatimes.com/watch?v=Oy17dtyskyU The ad for "Herpexia"backlot/gallery/supernatural/2008/10/19/Supernatural_jared_mini_bike See pics of them] is a spoof during the filming of the [http://www[4.youtube.com/watch?v=_iLTfG75s6g ad for Valtrex06 Yellow Fever]] genital herpes treatment.''

In this episode, great care went into choosing the music. [http://xfinity.comcast.net/blogs/tv/2009/11/03/the-big-tease-scoop-on-greys-chuck-supernatural-and-more/ Kripke said ], "We share a music supervisor with ''Grey’s'', [http://en.wikipedia.org/wiki/Alexandra_Patsavas Alex Patsavas], so she made sure we had the perfect type of songs. I think a few may have even been used on ''Grey's''.'" ([http://xfinity.comcast.net/blogs/tv/2009/11/03/the-big-tease-scoop-on-greys-chuck-supernatural-and-more/ Source)].

Dean drives Jensen and Patrick "McDreamy" Dempsey both appeared in the Marilyn Monroe biopic ''Blonde'' - [[Sampala]] past http://www.youtube.com/watch?v=5oZC24Ph-xY a sign that says "Centennial Point Wilderness Area." Centennial Highway was scene from the highway on which [[Woman in White]] [[Constance Welch]] would pick up her victims in [[1movie.01 Pilot]].

Jensen and Patrick "McDreamy" Dempsey both appeared in Dean drives the Marilyn Monroe biopic ''Blonde'' - [http://www.youtube.com/watch?v=5oZC24Ph-xY [Sampala]] past a scene from the movie]sign that says "Centennial Point Wilderness Area.}}{{TriviaQuote |Text=The mini bikes " Centennial Highway was the boys are seen riding highway on which [[Woman in the opening credits are actually mini bikes they ride around on set.White]] [[http://photos.latimes.com/backlot/gallery/supernatural/2008/10/19/Supernatural_jared_mini_bike See pics of themConstance Welch]] during the filming of would pick up her victims in [[41.06 Yellow Fever01 Pilot]].''

* In June 2010, The CW submitted this episode, along with [[5.04 The End]] for consideration for an Emmy nomination.* [http://www.youtube.com/watch?v=j9o437wX-B4 "Soon" promo] contains spoilers for 5.06, 5.07 and 5.08* [http://ausiellofiles.ew.com/2009/10/13/supernatural-first-look-sam-and-dean-check-into-seattle-grace/ Promo pic and synopsisSynopsis] by Ausiello* [http://s889.photobucket.com/albums/ac98/Superwiki/season5ep8/ Promo pics]* [http://www.youtube.com/watch?v=e-DRdjbcFPU Promo clip]* [http://www.youtube.com/watch?v=Gg6y_JnHbFA Clip from ep]* [http://xfinity.comcast.net/blogs/tv/2009/11/03/the-big-tease-scoop-on-greys-chuck-supernatural-and-more/ Some more teasers about the episode particularly the musicEpisode Spoilers] from Matt Mitovich

* [http://s889.photobucket.com/albums/ac98/Superwiki/season5ep8/ Promo Pics]* [http://www.youtube.com/watch?v=kMW9NFSTNdQ Space TV promo clipj9o437wX-B4 "Soon" Promo]* [http://www.youtube.com/watch?v=54asJRBOIqg Second clip from epe-DRdjbcFPU Promo Clip]* [http://www.youtube.com/watch?v=46gPNtEIp_U A third clip from epkMW9NFSTNdQ Space TV Promo] }}