- The story follows an infamous Western outlaw Harland Rust (Alec Baldwin) has had a bounty on his head for as long as he can remember. When his estranged 13-year-old grandson Lucas (Noon) is convicted of an accidental murder and sentenced to hang, Rust travels to Kansas to break him out of prison. Together, the two fugitives must outrun the legendary U.S. Marshal Wood Helm (Ackles) and bounty-hunter Fenton “Preacher” Lang (Travis Fimmel) who are hot on their tail. Deeply buried secrets rise from the ashes and an unexpected familial bond begins to form as the mismatched duo tries to survive the merciless American Frontier.
- Initial announcement about the project was back on 29 May, 2020, however filming was delayed due to the pandemic.
Death during filming
On 22 October it was reported that there had been an on-set shooting accident, where Alec Baldwin discharged a prop gun that killed Director of Photographer Halyna Hutchins, and injured writer/director Joel Souza. It is unknown whether Jensen was on set at the time.
- More news on the shooting and pre-existing safety issues on set by the LA Times
- A fundraiser for the family of Halyna Hutchins has been set up by the International Cinematographers Guild.
- Haylna's husband has set up a memorial scholarship in her name with the American Film Institute.
- Eric Kripke calls for filmmakers to replace not use real guns on set: "Someone hurt or killed on my set is my worst nightmare. Sending love to Halyna Hutchins' family, @JensenAckles, cast & crew of "Rust." I'm so sorry. In her memory, a simple, easy pledge: no more guns with blanks on any of my sets ever. We'll use VFX muzzle flashes. Who's with me?"
- Prop Master from Walker explains gun safety on set