Dr. Sexy, M.D.
Sam: What are you watching?
Dean: A hospital show - Dr. Sexy, M.D.. I think it's based on a book.Sam: When did you hit menopause?
– Sam and Dean, 5.08 Changing Channels
Dr. Sexy, M.D. is the name of a fictitious hospital drama, based on a series of books, that has featured in Supernatural. It is a hospital drama set at Seattle Mercy Hospital and is a send-up of Grey's Anatomy a medical drama which aired opposite Supernatural in the U.S. on Thursday nights, revolving around the love lives of the staff of Seattle Grace Hospital. The name is a reference to Dr. Derek Shepherd, played by Patrick Dempsey, who is nicknamed "McDreamy" by other characters Grey's Anatomy.
Dean is a big fan of the show.
- Dr. Sexy - a doctor, sexy because of his signature cowboy boots.
- Dr. Ellen Piccolo - a "sexy yet earnest" doctor.
- Dr. Wang - a "sexy but arrogant" heart surgeon.
- Dr. S. Winchester - a cerebrovascular neurosurgeon (in The Trickster's version).
- Dr. D. Winchester (in The Trickster's version).
- A nameless "sexy but neurotic" doctor.
- Johnny Drake - a ghost in the mind of the "sexy but neurotic" doctor.
- Mrs. Biehl - a patient in need of a face transplant.
- Mr. Biehl - Mrs. Biehl's husband.
4.18 The Monster at the End of This Book
Sera Siege mentions Dr. Sexy, M.D. as one of the reasons the Supernatural books went out of print: "All anybody wants to read anymore is that romance crap. You know -- 'Doctor Sexy, M.D.'? Please."
5.08 Changing Channels
Gabriel traps Sam and Dean in a fantasy realm, where one of the TV shows they are trapped inside is Dr. Sexy, M.D. The scenes and melodramatic dialogue mimic that of Grey's Anatomy. Dean works out that Gabriel is disguised as Dr. Sexy because he is wearing the wrong shoes: "The thing that makes Dr. Sexy sexy is the fact that he wears cowboy boots. Not tennis shoes."
7.02 Hello, Cruel World
One of the Leviathans -- Annie -- sees a snippet of the show, and that gives it the inspiration to use a hospital as a source of human organs for food. It even refers to itself as a "Doctor Sexy" to assert its authority.